Stag2^tm1.1Htyu
Targeted Allele Detail

Summary

• Symbol: Stag2^tm1.1Htyu
• Name: STAG2 cohesin complex component; targeted mutation 1.1, Hongtao Yu
• MGI ID: MGI:7335238
• Synonyms: Stag2^f
• Gene: Stag2 Location: ChrX:41238194-41366062 bp, + strand Genetic Position: ChrX, 23.19 cM, cytoband A2
• Alliance: Stag2^tm1.1Htyu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:328115
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 8 and an frt-flanked PGK-neo cassette and second loxP site were inserted downstream of exon 8. The neomycin selection cassette was removed via flp-mediated recombination. (J:328115)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stag2 Mutation: 14 strains or lines available

References

• Original: J:328115 Cheng N, et al., STAG2 promotes the myelination transcriptional program in oligodendrocytes. Elife. 2022 Aug 12;11:e77848
• All: 1 reference(s)