Ddx3x^tm1Tmo
Targeted Allele Detail

Summary

• Symbol: Ddx3x^tm1Tmo
• Name: DEAD box helicase 3, X-linked; targeted mutation 1, Tarik Moroy
• MGI ID: MGI:7335163
• Gene: Ddx3x Location: ChrX:13147261-13160222 bp, + strand Genetic Position: ChrX, 8.17 cM
• Alliance: Ddx3x^tm1Tmo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327831
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. (J:327831)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx3x Mutation: 10 strains or lines available

References

• Original: J:327831 Lacroix M, et al., The X-Linked Helicase DDX3X Is Required for Lymphoid Differentiation and MYC-Driven Lymphomagenesis. Cancer Res. 2022 Sep 2;82(17):3172-3186
• All: 1 reference(s)