Ficd^em1Orth
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ficd^em1Orth
• Name: FIC domain containing; endonuclease-mediated mutation 1, Kim Orth
• MGI ID: MGI:7330316
• Synonyms: Fic^fl
• Gene: Ficd Location: Chr5:113873864-113878661 bp, + strand Genetic Position: Chr5, 55.55 cM
• Alliance: Ficd^em1Orth page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Using CRISPR/Cas9-targeting, one loxP site upstream and another loxP site downstream of exon 3 of the Ficd gene were inserted. (J:327310)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ficd Mutation: 19 strains or lines available

References

• Original: J:327310 Casey AK, et al., Fic-mediated AMPylation tempers the unfolded protein response during physiological stress. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2208317119
• All: 1 reference(s)