Jag1^em5Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Jag1^em5Lutzy
• Name: jagged 1; endonuclease-mediated mutation 5, Cathy Lutz
• MGI ID: MGI:7329948
• Synonyms: Jag1 8 nt deletion
• Gene: Jag1 Location: Chr2:136923371-136958440 bp, - strand
• Alliance: Jag1^em5Lutzy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 genome editing was originally designed to introduce a S577R point mutation (AGC to AGA) and a silent mutation. DNA sequencing of the targeted region identified a founder instead harboring an 8 nucleotide deletion (indel mutation) after the sequence encoding amino acid 578. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Jag1 Mutation: 78 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)