Ppip5k2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppip5k2^em1Cya
• Name: diphosphoinositol pentakisphosphate kinase 2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7328441
• Synonyms: Ppip5k2^em1cyagen
• Gene: Ppip5k2 Location: Chr1:97633773-97698136 bp, - strand Genetic Position: Chr1, 47.76 cM
• Alliance: Ppip5k2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination created a deletion spanning a region including exons 3, 4, and 5. (J:327076)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppip5k2 Mutation: 75 strains or lines available

References

• Original: J:327076 Du C, et al., Renal Klotho and inorganic phosphate are extrinsic factors that antagonistically regulate hematopoietic stem cell maintenance. Cell Rep. 2022 Feb 15;38(7):110392
• All: 1 reference(s)