Mcpt8tm1.1(cre)Ics
Targeted Allele Detail
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Symbol: |
Mcpt8tm1.1(cre)Ics |
Name: |
mast cell protease 8; targeted mutation 1.1, Mouse Clinical Institute |
MGI ID: |
MGI:7327249 |
Synonyms: |
CT-M8, Mcpt8-Cre-tdTomato, Mcpt8CT, Mcpt8tm1Ics |
Gene: |
Mcpt8 Location: Chr14:56319623-56322730 bp, - strand Genetic Position: Chr14, 28.19 cM
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Alliance: |
Mcpt8tm1.1(cre)Ics page
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Germline Transmission: |
Earliest citation of germline transmission:
J:326806
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Recombinase, Reporter) |
Mutation: |
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Insertion
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Mcpt8tm1.1(cre)Ics expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The targeting construct inserted into exon 5 upstream of the stop codon an IRES, cre recombinase gene, T2A, Td-Tomato reporter gene, and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette.
(J:326806)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Mcpt8
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mcpt8 Mutation: |
23 strains or lines available
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Original: |
J:326806 Tchen J, et al., CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development. Front Immunol. 2022;13:900532 |
All: |
1 reference(s) |
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