Nfe2l2^tm1Gmdn
Targeted Allele Detail

Summary

• Symbol: Nfe2l2^tm1Gmdn
• Name: nuclear factor, erythroid derived 2, like 2; targeted mutation 1, Gina M DeNicola
• MGI ID: MGI:7327101
• Synonyms: LSL-Nrf2D29H
• Gene: Nfe2l2 Location: Chr2:75505857-75534985 bp, - strand Genetic Position: Chr2, 44.75 cM
• Alliance: Nfe2l2^tm1Gmdn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326865
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: A STOP cassette flanked by loxP sites was inserted into intron 1 and codon 29 in endogenous exon 2 was mutated from an aspartic acid to a histidine. (J:326865)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfe2l2 Mutation: 94 strains or lines available

Notes

ES cells = C10 (modified V6.5 containing Col1a1^{tm2(tetO-Pou5f1)Jae})

References

• Original: J:326865 DeNicola GM, Direct Data Submission for Nfe2l2 Allele. MGI Direct Data Submission. 2022
• All: 5 reference(s)