Nedd9^tm1.1Cya
Targeted Allele Detail

Summary

• Symbol: Nedd9^tm1.1Cya
• Name: neural precursor cell expressed, developmentally down-regulated gene 9; targeted mutation 1.1, Cyagen Biosciences
• MGI ID: MGI:7316596
• Synonyms: Nedd9^fl
• Gene: Nedd9 Location: Chr13:41463392-41640836 bp, - strand Genetic Position: Chr13, 20.43 cM
• Alliance: Nedd9^tm1.1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326296
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 4 - 7 were floxed and a ROX flanked neo cassette was inserted via homologous recombination. Recombinase mediated recombination removed the neo cassette. (J:326296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nedd9 Mutation: 34 strains or lines available

References

• Original: J:326296 Rusyn L, et al., The scaffold protein NEDD9 is necessary for leukemia-cell migration and disease progression in a mouse model of chronic lymphocytic leukemia. Leukemia. 2022 Jul;36(7):1794-1805
• All: 1 reference(s)