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Tg(NKX2-5-lacZ)C3-2Abl
Transgene Detail
Summary
Symbol: Tg(NKX2-5-lacZ)C3-2Abl
Name: transgene insertion C3-2, Andrew Lassar
MGI ID: MGI:7314913
Transgene: Tg(NKX2-5-lacZ)C3-2Abl  Location: unknown  
Alliance: Tg(NKX2-5-lacZ)C3-2Abl page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA subpart of the chicken second heart field (SHF) NK2 homeobox 5 enhancer (cardiac activating region 3 (CAR3); nucleotides 976-3047 after transcriptional start site) was used to drive the expression of a reporter gene cassette containing the hsp68 promoter, lacZ beta-galactosidase gene and poly(A) signal sequences. (J:326594)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:326594 Lee KH, et al., SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer. Development. 2004 Oct;131(19):4709-23
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory