Rr203^em1Jfz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr203^em1Jfz
• Name: regularoty region 203; endonuclease-mediated mutation 1, Jinfang Zhu
• MGI ID: MGI:7314860
• Synonyms: Tbx21^deltaCNS-8.5
• Gene: Rr203 Location: Chr11:97014283-97014758 bp Genetic Position: Chr11, Syntenic
• Alliance: Rr203^em1Jfz page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted the conserved non-coding sequence 8.5 kb upstream of the Tbx21 transcriptional start site. (J:325490)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr203 Mutation: 0 strains or lines available

References

• Original: J:325490 Fang D, et al., Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation. Immunity. 2022 Apr 12;55(4):639-655.e7
• All: 1 reference(s)