Foxf2^tm1.1Vvk
Targeted Allele Detail

Summary

• Symbol: Foxf2^tm1.1Vvk
• Name: forkhead box F2; targeted mutation 1.1, Vladimir V Kalinichenko
• MGI ID: MGI:7314523
• Synonyms: Foxf2^fl
• Gene: Foxf2 Location: Chr13:31809799-31815386 bp, + strand Genetic Position: Chr13, 13.48 cM, cytoband A4
• Alliance: Foxf2^tm1.1Vvk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279187
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT and loxP flanked neo cassette was inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. (J:279187)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxf2 Mutation: 20 strains or lines available

References

• Original: J:279187 Bolte C, et al., Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development. J Biol Chem. 2015 Mar 20;290(12):7563-75
• All: 2 reference(s)