Rimklb^tm1.1Meck
Targeted Allele Detail

Summary

• Symbol: Rimklb^tm1.1Meck
• Name: ribosomal modification protein rimK-like family member B; targeted mutation 1.1, Matthias Eckhardt
• MGI ID: MGI:7312210
• Gene: Rimklb Location: Chr6:122424255-122464021 bp, - strand Genetic Position: Chr6, 57.55 cM, cytoband F2
• Alliance: Rimklb^tm1.1Meck page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326420
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct floxed exon 5. Cre-mediated recombination removed exon 5. (J:326420)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rimklb Mutation: 63 strains or lines available

References

• Original: J:326420 Wang-Eckhardt L, et al., Citrylglutamate synthase deficient male mice are subfertile with impaired histone and transition protein 2 removal in late spermatids. Biochem J. 2022 May 13;479(9):953-972
• All: 1 reference(s)