Fermt3^tm1.1Mos
Targeted Allele Detail

Summary

• Symbol: Fermt3^tm1.1Mos
• Name: fermitin family member 3; targeted mutation 1.1, Markus Moser
• MGI ID: MGI:7312167
• Gene: Fermt3 Location: Chr19:6976326-6996837 bp, - strand Genetic Position: Chr19, 5.13 cM
• Alliance: Fermt3^tm1.1Mos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280278
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutation: Insertion
• Mutation details: A triple Flag tag sequence was inserted into exon 2 after the codon for methionine at position 4. In addition, a loxP-flanked neomycin resistance cassette was introduced into intron 2. Cre-mediated recombination removed the neomycin cassette. (J:280278)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fermt3 Mutation: 30 strains or lines available

References

• Original: J:280278 Klapproth S, et al., A kindlin-3-leupaxin-paxillin signaling pathway regulates podosome stability. J Cell Biol. 2019 Oct 7;218(10):3436-3454
• All: 1 reference(s)