Sost^{em3(SOST)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sost^{em3(SOST)Smoc}
• Name: sclerostin; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7292535
• Synonyms: Sost^{em1(hSOST)Smoc}
• Gene: Sost Location: Chr11:101853284-101857841 bp, - strand Genetic Position: Chr11, 65.48 cM, cytoband D
• Alliance: Sost^{em3(SOST)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Sost^{em3(SOST)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SOST (50964)

  Sost	(MGI:1921749)

• Mutation details: The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sost Mutation: 34 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)