Col1a1^{em2(tetO-cas9*)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Col1a1^{em2(tetO-cas9*)Smoc}
• Name: collagen, type I, alpha 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7289073
• Synonyms: Col1a1^{em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc}
• Gene: Col1a1 Location: Chr11:94827050-94843868 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D
• Alliance: Col1a1^{em2(tetO-cas9*)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Endonuclease, Inducible, Reporter)
• Mutation: Insertion
• Mutation details: These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa). (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Col1a1 Mutation: 166 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)