Cd74^{em1(CD74)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd74^{em1(CD74)Smoc}
• Name: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7288856
• Synonyms: Cd74^{em1(hCD74)Smoc}
• Gene: Cd74 Location: Chr18:60936921-60945724 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Cd74^{em1(CD74)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Cd74^{em1(CD74)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD74 (972)

  Cd74	(MGI:96534)

• The endogenous mouse Cd74 gene was replaced by human CD74 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd74 Mutation: 36 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)