Is(19BORCS7-AS3MT)1Bhk
Targeted Allele Detail

Summary

• Symbol: Is(19BORCS7-AS3MT)1Bhk
• Name: insertion, Chr 19, Beverly H Koller 1
• MGI ID: MGI:7287723
• Gene: Is(19BORCS7-AS3MT)1Bhk Location: unknown Genetic Position: Chr19, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:292196
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Is(19BORCS7-AS3MT)1Bhk involves 2 genes/genome features (Borcs7, As3mt) View all
• Mutation details: The targeting construct replaced the 60,908 bp segment extending from chr19:46,683,032 to 46,744,011 with a 59,261-bp segment of human DNA extending from chr10:102,845,563 to 102,904,823 and a floxed neomycin resistance cassette. (J:292196)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Is(19BORCS7-AS3MT)1Bhk Mutation: 2 strains or lines available

References

• Original: J:292196 Koller BH, et al., Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement. Environ Health Perspect. 2020 Aug;128(8):87003
• All: 2 reference(s)