Ptgds^tm1.1Hsun
Targeted Allele Detail

Summary

• Symbol: Ptgds^tm1.1Hsun
• Name: prostaglandin D2 synthase (brain); targeted mutation 1.1, Hong Sun
• MGI ID: MGI:7286089
• Synonyms: L-PGDS^flox
• Gene: Ptgds Location: Chr2:25356721-25360058 bp, - strand Genetic Position: Chr2, 17.28 cM
• Alliance: Ptgds^tm1.1Hsun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:325367
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and self-deletion anchor site-flanked neomycin selection cassette was inserted in the intron upstream of exon 2 and a second loxP site downstream of exon 5. The self-excising neomycin selection cassette is absent in this allele. (J:325367)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptgds Mutation: 16 strains or lines available

References

• Original: J:325367 Li C, et al., Protective Effect of Low-Dose Alcohol Consumption against Post-Ischemic Neuronal Apoptosis: Role of L-PGDS. Int J Mol Sci. 2021 Dec 23;23(1)
• All: 1 reference(s)