Gt(ROSA)26Sor^{em47(CAG-Dlx2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em47(CAG-Dlx2)Smoc}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 47, Shanghai Model Organisms Center
• MGI ID: MGI:7286075
• Synonyms: Rosa26^{CAG-LSL-Dlx2-3xFlag}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em47(CAG-Dlx2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{em47(CAG-Dlx2)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Dlx2 (MGI:94902)

• Mutation details: CRISPR/cas9 mediated recombination introduced a construct consisting of a CAG promoter, floxed stop cassette, mouse Dlx2 gene with a 3X Flag tag, and a woodchuck hepatitis virus post-transcriptional regulatory element into intron 1. (J:324244)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1060 strains or lines available

References

• Original: J:324244 Sun J, et al., A Neural Crest-specific Overexpression Mouse Model Reveals the Transcriptional Regulatory Effects of Dlx2 During Maxillary Process Development. Front Physiol. 2022;13:855959
• All: 1 reference(s)