Osr1^em1Tkto
Endonuclease-mediated Allele Detail

Summary

• Symbol: Osr1^em1Tkto
• Name: odd-skipped related transcription factor 1; endonuclease-mediated mutation 1, Tatsuya Takemoto
• MGI ID: MGI:7286018
• Gene: Osr1 Location: Chr12:9624442-9631500 bp, + strand Genetic Position: Chr12, 4.05 cM
• Alliance: Osr1^em1Tkto page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the coding sequence. (J:310902)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Osr1 Mutation: 16 strains or lines available

References

• Original: J:310902 Hayashi S, et al., The nephric mesenchyme lineage of intermediate mesoderm is derived from Tbx6-expressing derivatives of neuro-mesodermal progenitors via BMP-dependent Osr1 function. Dev Biol. 2021 Oct;478:155-162
• All: 1 reference(s)