Cd63^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd63^em1Cya
• Name: CD63 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7284354
• Synonyms: Cd63^em1Cgen, Cd63^{em(loxp-mCherry-loxp-eGFP)3}
• Gene: Cd63 Location: Chr10:128736858-128748691 bp, + strand Genetic Position: Chr10, 77.19 cM
• Alliance: Cd63^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: Using the CRISPR/Cas9-mediated knock-in system, the loxp-cc-mCherry-polyA-loxp-cc-eGFP cassette was inserted into the Cd63 gene at the site of the stop codon in exon 8 of the Cd63 gene. (J:324882)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd63 Mutation: 19 strains or lines available

References

• Original: J:324882 Wang ZX, et al., Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox. Nat Commun. 2022 Mar 18;13(1):1453
• All: 1 reference(s)