Tbpl1^tm1.1Idvd
Targeted Allele Detail

Summary

• Symbol: Tbpl1^tm1.1Idvd
• Name: TATA box binding protein-like 1; targeted mutation 1.1, Irwin Davidson
• MGI ID: MGI:7280778
• Synonyms: Trf2^tag
• Gene: Tbpl1 Location: Chr10:22579778-22607837 bp, - strand Genetic Position: Chr10, 10.25 cM, cytoband A3
• Alliance: Tbpl1^tm1.1Idvd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324539
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutation: Insertion
• Mutation details: A 6xHis-Tev-3xFlag tag was inserted in-frame to the coding sequences for the C-terminus of the protein. The neomycin resistance cassette was removed via FLP-mediated recombination in the germline. (J:324539)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbpl1 Mutation: 12 strains or lines available

References

• Original: J:324539 Martianov I, et al., TRF2 is recruited to the pre-initiation complex as a testis-specific subunit of TFIIA/ALF to promote haploid cell gene expression. Sci Rep. 2016 Aug 31;6:32069
• All: 1 reference(s)