Atg16l2^tm1.1Xav
Targeted Allele Detail

Summary

• Symbol: Atg16l2^tm1.1Xav
• Name: autophagy related 16 like 2; targeted mutation 1, Ramnik Xavier
• MGI ID: MGI:7279148
• Synonyms: Atg16l2^delta
• Gene: Atg16l2 Location: Chr7:100935521-100951474 bp, - strand Genetic Position: Chr7, 54.54 cM
• Alliance: Atg16l2^tm1.1Xav page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280792
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 x C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP-flanked neomycin resistance gene replaced the entire coding region of the gene. The neomycin resistance gene was subsequently removed via Cre-mediated recombination in the germline. (J:280792)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg16l2 Mutation: 41 strains or lines available

References

• Original: J:280792 Khor B, et al., Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1. J Immunol. 2019 Oct 1;203(7):1820-1829
• All: 1 reference(s)