Get3^tm1.1Heed
Targeted Allele Detail

Summary

• Symbol: Get3^tm1.1Heed
• Name: guided entry of tail-anchored proteins factor 3, ATPase; targeted mutation 1, Helena Edlund
• MGI ID: MGI:7278816
• Synonyms: Asna1^flox
• Gene: Get3 Location: Chr8:85744560-85751910 bp, - strand Genetic Position: Chr8, 41.48 cM, cytoband C3-D1
• Alliance: Get3^tm1.1Heed page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246324
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 2. An frt-flanked neomycin selection cassette inserted in intron 3 was removed via FLP-mediated recombination in the germline. (J:246324)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Get3 Mutation: 20 strains or lines available

References

• Original: J:246324 Norlin S, et al., Asna1/TRC40 Controls beta-Cell Function and Endoplasmic Reticulum Homeostasis by Ensuring Retrograde Transport. Diabetes. 2016 Jan;65(1):110-9
• All: 2 reference(s)