Basp1^tm1.2Cya
Targeted Allele Detail

Summary

• Symbol: Basp1^tm1.2Cya
• Name: brain abundant, membrane attached signal protein 1; targeted mutation 1.2, Cyagen Biosciences
• MGI ID: MGI:7266657
• Synonyms: BASP1 KO, Basp1^tm1.2Cgen
• Gene: Basp1 Location: Chr15:25363363-25413850 bp, - strand Genetic Position: Chr15, 9.16 cM
• Alliance: Basp1^tm1.2Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283091
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2 was flanked by loxP sites and an frt-flanked neomycin selection cassette. The selection cassette was removed via FLP1-mediated recombination, leaving loxP sites flanking exon 2. Subsequent Cre-mediated recombination in the germline removed exon 2. (J:283091)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Basp1 Mutation: 11 strains or lines available

References

• Original: J:283091 Gao Y, et al., The WT1-BASP1 complex is required to maintain the differentiated state of taste receptor cells. Life Sci Alliance. 2019 Jun;2(3)
• All: 1 reference(s)