Mixl1^tm1.2Hadj
Targeted Allele Detail

Summary

• Symbol: Mixl1^tm1.2Hadj
• Name: Mix paired-like homeobox; targeted mutation 1.2, Anna-Katerina Hadjantonakis
• MGI ID: MGI:7266383
• Synonyms: Mixl1 KO
• Gene: Mixl1 Location: Chr1:180520608-180524599 bp, - strand Genetic Position: Chr1, 84.46 cM
• Alliance: Mixl1^tm1.2Hadj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:321351
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP sites and a loxP-flanked neomycin selection cassette was inserted to flank exon 2. Cre-mediated recombination in ES cells resulted in the germline resulted in the deletion of exon2 and the selection cassette. (J:321351)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mixl1 Mutation: 20 strains or lines available

References

• Original: J:321351 Pulina MV, et al., A conditional mutant allele for analysis of Mixl1 function in the mouse. Genesis. 2014 May;52(5):417-23
• All: 1 reference(s)