Tspoap1^tm1.1Sud
Targeted Allele Detail

Summary

• Symbol: Tspoap1^tm1.1Sud
• Name: TSPO associated protein 1; targeted mutation 1.1, Thomas C Sudhof
• MGI ID: MGI:7265068
• Synonyms: RIM-BP1 KO
• Gene: Tspoap1 Location: Chr11:87651367-87676754 bp, + strand Genetic Position: Chr11, 52.21 cM
• Alliance: Tspoap1^tm1.1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227659
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 16 followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 16. Cre-mediated recombination in the germline resulted in the deletion of exon 16 and the resistance cassette. (J:227659)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspoap1 Mutation: 49 strains or lines available

References

• Original: J:227659 Acuna C, et al., RIM-BPs Mediate Tight Coupling of Action Potentials to Ca(2+)-Triggered Neurotransmitter Release. Neuron. 2015 Sep 23;87(6):1234-47
• All: 3 reference(s)