Mecp2^tm1Qcha
Targeted Allele Detail

Summary

• Symbol: Mecp2^tm1Qcha
• Name: methyl CpG binding protein 2; targeted mutation 1, Qiang Chang
• MGI ID: MGI:7264414
• Synonyms: Flag-Mecp2^S421A
• Gene: Mecp2 Location: ChrX:73070198-73129296 bp, - strand Genetic Position: ChrX, 37.63 cM
• Alliance: Mecp2^tm1Qcha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175890
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Epitope tag, Modified isoform(s))
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: Mice express Flag-tagged mutant MeCP2 with a S421A mutation from the endogenous Mecp2 locus. Details were not specified. (J:175890)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mecp2 Mutation: 41 strains or lines available

References

• Original: J:175890 Li H, et al., Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory. Nat Neurosci. 2011 Aug;14(8):1001-8
• All: 1 reference(s)