Lpar4^tm1Cjch
Targeted Allele Detail

Summary

• Symbol: Lpar4^tm1Cjch
• Name: lysophosphatidic acid receptor 4; targeted mutation 1, Ching-Kang Chen
• MGI ID: MGI:7261375
• Synonyms: lpa4 KO
• Gene: Lpar4 Location: ChrX:105964231-105977505 bp, + strand Genetic Position: ChrX, 47.39 cM
• Alliance: Lpar4^tm1Cjch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:294246
• Parent Cell Line: HZ2.2 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic segment containing the 3 end of intron 2 and the 5 portion (with the complete coding sequence) of exon 3 was replaced with a neomycin selection cassette. (J:294246)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lpar4 Mutation: 5 strains or lines available

References

• Original: J:294246 Lee Z, et al., Role of LPA4/p2y9/GPR23 in negative regulation of cell motility. Mol Biol Cell. 2008 Dec;19(12):5435-45
• All: 4 reference(s)