Meis2^em1Zzz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Meis2^em1Zzz
• Name: Meis homeobox 2; endonuclease-mediated mutation 1, Zhuangzhi Zhang
• MGI ID: MGI:7260220
• Synonyms: hs599^-
• Gene: Meis2 Location: Chr2:115693545-115896320 bp, - strand Genetic Position: Chr2, 58.28 cM
• Alliance: Meis2^em1Zzz page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intergenic deletion
• Mutation details: Using CRISPR/Cas9 genome editing in fertilized eggs, 1731 bp enhancer Dlx1/2 binding regions near the Meis2 gene named hs599 were deleted. (J:321980)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meis2 Mutation: 29 strains or lines available

References

• Original: J:321980 Su Z, et al., Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035
• All: 1 reference(s)