Gpr84^em1Jluo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr84^em1Jluo
• Name: G protein-coupled receptor 84; endonuclease-mediated mutation 1, Jian Luo
• MGI ID: MGI:7260178
• Gene: Gpr84 Location: Chr15:103216662-103219039 bp, - strand Genetic Position: Chr15, 58.88 cM
• Alliance: Gpr84^em1Jluo page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 176-bp deletion. (J:322343)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr84 Mutation: 31 strains or lines available

References

• Original: J:322343 Wang F, et al., Fatty acid sensing GPCR (GPR84) signaling safeguards cartilage homeostasis and protects against osteoarthritis. Pharmacol Res. 2021 Feb;164:105406
• All: 1 reference(s)