Tg(CD40)1Rav
Transgene Detail

Summary

• Symbol: Tg(CD40)1Rav
• Name: transgene insertion 1, Jeffrey V Ravetch
• MGI ID: MGI:7260119
• Synonyms: hCD40 Tg
• Transgene: Tg(CD40)1Rav Location: unknown
• Alliance: Tg(CD40)1Rav page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD40)1Rav expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD40 (958)

  Cd40	(MGI:88336)

• Mutation details: Linearized RP11-177B15 human bacterial artificial chromosome DNA, containing the CD40 gene, was used to create transgenic mice by embryo injection. (J:232332)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:232332 Dahan R, et al., Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcgammaR Engagement. Cancer Cell. 2016 Jun 13;29(6):820-31
• All: 5 reference(s)