Hmox1^tm1.1Cdap
Targeted Allele Detail

Summary

• Symbol: Hmox1^tm1.1Cdap
• Name: heme oxygenase 1; targeted mutation 1.1, Claude A Piantadosi
• MGI ID: MGI:7258111
• Synonyms: Hmox1^fl
• Gene: Hmox1 Location: Chr8:75820249-75827217 bp, + strand Genetic Position: Chr8, 35.59 cM, cytoband C1
• Alliance: Hmox1^tm1.1Cdap page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322124
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector a loxP site into intron 2 and a loxP site with an FRT-flanked neomycin-resistance cassette downstream of exon 5. Flp-mediated recombination removed the selection cassette. (J:322124)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hmox1 Mutation: 33 strains or lines available

References

• Original: J:322124 Suliman HB, et al., Mitochondrial quality-control dysregulation in conditional HO-1(-/-) mice. JCI Insight. 2017 Feb 9;2(3):e89676
• All: 2 reference(s)