Procr^{tm3.1(rtTA)Yaz}
Targeted Allele Detail

Summary

• Symbol: Procr^{tm3.1(rtTA)Yaz}
• Name: protein C receptor, endothelial; targeted mutation 3.1, Yi Arial Zeng
• MGI ID: MGI:7256872
• Synonyms: Procr-rtTA
• Gene: Procr Location: Chr2:155593037-155597391 bp, + strand Genetic Position: Chr2, 77.26 cM, cytoband H1-3
• Alliance: Procr^{tm3.1(rtTA)Yaz} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:281673
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: The reverse tetracycline controlled transactivator (rtTA) and frt-flanked neo was inserted at the ATG start codon of the Procr gene by homologous recombination. The frt-flanked neo was removed by Flp recombinase expression. (J:281673)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Procr Mutation: 16 strains or lines available

References

• Original: J:281673 Wang J, et al., Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium. Nat Commun. 2019 Oct 31;10(1):4966
• All: 2 reference(s)