Ido1^tm1.1Rhmc
Targeted Allele Detail

Summary

• Symbol: Ido1^tm1.1Rhmc
• Name: indoleamine 2,3-dioxygenase 1; targeted mutation 1.1, Robert H McCusker
• MGI ID: MGI:7256735
• Synonyms: Ido1fl
• Gene: Ido1 Location: Chr8:25074148-25086987 bp, - strand Genetic Position: Chr8, 12.76 cM
• Alliance: Ido1^tm1.1Rhmc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322052
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 5' of the second exon and a second loxP was inserted 3' of the fourth exon. An frt-flanked neomycin selection cassette was removed via flp-mediated recombination leaving exons 2-4 floxed. (J:322052)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ido1 Mutation: 27 strains or lines available

References

• Original: J:322052 Tousif S, et al., Indoleamine 2, 3-Dioxygenase Promotes Aryl Hydrocarbon Receptor-Dependent Differentiation Of Regulatory B Cells in Lung Cancer. Front Immunol. 2021;12:747780
• All: 4 reference(s)