Gt(ROSA)26Sortm1(GSDMB_i2,-EGFP)Gmbu
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(GSDMB_i2,-EGFP)Gmbu |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Gema Moreno-Bueno |
MGI ID: |
MGI:7256399 |
Synonyms: |
R26-STOP-GB2 |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(GSDMB_i2,-EGFP)Gmbu page
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Germline Transmission: |
Earliest citation of germline transmission:
J:321835
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6 x 129
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Allele Type: |
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Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Mutation details: A loxP-flanked PGK-neomycin-STOP cassette, the HA-tagged human Gasdermin B isoform 2, IRES, and EGFP were inserted into the locus.
(J:321835)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
944 strains or lines available
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Original: |
J:321835 Sarrio D, et al., Gasdermin-B Pro-Tumor Function in Novel Knock-in Mouse Models Depends on the in vivo Biological Context. Front Cell Dev Biol. 2022;10:813929 |
All: |
1 reference(s) |
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