Trim34a^em1Juwa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim34a^em1Juwa
• Name: tripartite motif-containing 34A; endonuclease-mediated mutation 1, Jun Wang
• MGI ID: MGI:6887748
• Synonyms: Trim34^-
• Gene: Trim34a Location: Chr7:103893664-103911441 bp, + strand Genetic Position: Chr7, 55.69 cM, cytoband F1
• Alliance: Trim34a^em1Juwa page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Using CRISPR/Cas9 technology, exon 2 of TRIM34 was targeted to generate the deletion. (J:321601)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim34a Mutation: 28 strains or lines available

References

• Original: J:321601 Wang X, et al., TRIM34 modulates influenza virus-activated programmed cell death by targeting Z-DNA-binding protein 1 for K63-linked polyubiquitination. J Biol Chem. 2022 Jan 20;298(3):101611
• All: 1 reference(s)