Tg(TcraPLP2,TcrbPLP2)183Lukl
Transgene Detail

Summary

• Symbol: Tg(TcraPLP2,TcrbPLP2)183Lukl
• Name: transgene insertion 183, Ludger Klein
• MGI ID: MGI:6886003
• Synonyms: TCR-PLP2
• Transgene: Tg(TcraPLP2,TcrbPLP2)183Lukl Location: unknown
• Alliance: Tg(TcraPLP2,TcrbPLP2)183Lukl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Transgenic TCR alpha and beta chain (co-inserted) derived from an MHC class II restricted TCR specific for myelin proteolipd protein (amino acids 172-183). (J:298760)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:298760 Wang L, et al., Epitope-Specific Tolerance Modes Differentially Specify Susceptibility to Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis. Front Immunol. 2017;8:1511
• All: 1 reference(s)