Lrrtm3^tm1.1Bcgen
Targeted Allele Detail

Summary

• Symbol: Lrrtm3^tm1.1Bcgen
• Name: leucine rich repeat transmembrane neuronal 3; targeted mutation 1.1, Biocytogen LLC
• MGI ID: MGI:6879505
• Synonyms: Lrrtm3^f
• Gene: Lrrtm3 Location: Chr10:63764276-63926034 bp, - strand Genetic Position: Chr10, 32.57 cM
• Alliance: Lrrtm3^tm1.1Bcgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:320789
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was introduced approximately 2 kb upstream of the 5' untranslated region and an FRT-flanked neomycin resistance gene and second loxP site were inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette leaving exons 1 and 2 floxed. (J:320789)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrrtm3 Mutation: 31 strains or lines available

References

• Original: J:320789 Kim J, et al., LRRTM3 regulates activity-dependent synchronization of synapse properties in topographically connected hippocampal neural circuits. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2110196119
• All: 1 reference(s)