Pilra^tm1.1Gne
Targeted Allele Detail

Summary

• Symbol: Pilra^tm1.1Gne
• Name: paired immunoglobin-like type 2 receptor alpha; targeted mutation 1.1, Genentech
• MGI ID: MGI:6872315
• Gene: Pilra Location: Chr5:137820214-137834540 bp, - strand Genetic Position: Chr5, 76.77 cM
• Alliance: Pilra^tm1.1Gne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:320371
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exons 1 and 2 with a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:320371)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pilra Mutation: 24 strains or lines available

References

• Original: J:320371 Sun Y, et al., PILRalpha negatively regulates mouse inflammatory arthritis. J Immunol. 2014 Jul 15;193(2):860-70
• All: 2 reference(s)