Tg(EEF1A1-IL15RA)1Nsat
Transgene Detail
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Symbol: |
Tg(EEF1A1-IL15RA)1Nsat |
Name: |
transgene insertion 1, Noriko Sato |
MGI ID: |
MGI:6867798 |
Synonyms: |
IL-15Ralpha Tg |
Transgene: |
Tg(EEF1A1-IL15RA)1Nsat Location: unknown
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Alliance: |
Tg(EEF1A1-IL15RA)1Nsat page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(EEF1A1-IL15RA)1Nsat expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
IL15RA (3601) |
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Mutation details: The transgenic construct contains from 5' to 3' a human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) promoter, a bovine preprolactin signal peptide, the human IL15RA (interleukin 15 receptor subunit alpha) mature coding sequence followed by an SV40 polyA signal.
(J:119072)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:119072 Sato N, et al., The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):588-93 |
All: |
1 reference(s) |
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