Clec4f^em1Lx
Endonuclease-mediated Allele Detail

Summary

• Symbol: Clec4f^em1Lx
• Name: C-type lectin domain family 4, member f; endonuclease-mediated mutation 1, Lijun Xia
• MGI ID: MGI:6867051
• Synonyms: Clec4f -4
• Gene: Clec4f Location: Chr6:83621524-83633098 bp, - strand Genetic Position: Chr6, 35.94 cM
• Alliance: Clec4f^em1Lx page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-mediated recombination created a 4 bp deletion (GCGG) in exon 2. (J:319933)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec4f Mutation: 26 strains or lines available

References

• Original: J:319933 Jiang Y, et al., Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice. Cell Death Differ. 2021 Nov;28(11):3009-3021
• All: 1 reference(s)