Cask^tm1Cya
Targeted Allele Detail

Summary

• Symbol: Cask^tm1Cya
• Name: calcium/calmodulin dependent serine protein kinase; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:6866991
• Synonyms: CASK^fl, Cask^tm1Cgen
• Gene: Cask Location: ChrX:13383319-13713020 bp, - strand Genetic Position: ChrX, 8.43 cM
• Alliance: Cask^tm1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319885
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 6 was flanked by loxP sites. (J:319885)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cask Mutation: 14 strains or lines available

References

• Original: J:319885 Liu X, et al., Specific Deletion of CASK in Pancreatic beta Cells Affects Glucose Homeostasis and Improves Insulin Sensitivity in Obese Mice by Reducing Hyperinsulinemia Running Title: beta Cell CASK Deletion Reduces Hyperinsulinemia. Diabetes. 2021 Oct 21
• All: 1 reference(s)