Atg5^em2Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atg5^em2Lutzy
• Name: autophagy related 5; endonuclease-mediated mutation 2, Cathy Lutz
• MGI ID: MGI:6864522
• Synonyms: Atg5 cKO
• Gene: Atg5 Location: Chr10:44144354-44240287 bp, + strand Genetic Position: Chr10, 23.24 cM
• Alliance: Atg5^em2Lutzy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 genome editing used crRNAs to insert loxP sites upstream (TAACTGTGCGGCCACATGAT; GTGTGTACTGACCAATCATG and downstream (GCTGAGCCAGACCTTTGTGC; GCACAAAGGTCTGGCTCAGC) regions of exon 4. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atg5 Mutation: 29 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)