Arid1a^tm1Yzhao
Targeted Allele Detail

Summary

• Symbol: Arid1a^tm1Yzhao
• Name: AT-rich interaction domain 1A; targeted mutation 1, Yong Zhao
• MGI ID: MGI:6864454
• Synonyms: Baf250a^f
• Gene: Arid1a Location: Chr4:133406319-133484080 bp, - strand Genetic Position: Chr4, 66.25 cM
• Alliance: Arid1a^tm1Yzhao page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:315376
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: Using homologous recombination in ES cells, the targeting vector inserted an frt-flanked IRES-nLacZ cassette, a 5' loxP site, and V5 tag upstream of exon 8 of the Arid1a gene and an additional 3' loxP site followed by F3 flanked Neo cassette was inserted downstream of exon 11. (J:315376)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arid1a Mutation: 181 strains or lines available

References

• Original: J:315376 Wu M, et al., Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node. Cell Res. 2014 Oct;24(10):1201-13
• All: 2 reference(s)