Gt(ROSA)26Sor^{tm1.1(CAG-ASTN2/PAPPA)Cya}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(CAG-ASTN2/PAPPA)Cya}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Cyagen Biosciences
• MGI ID: MGI:6863916
• Synonyms: A-PaschiRNA^flox, Gt(ROSA)26Sor^{tm1.1(CAG-ASTN2/PAPPA)Cgen}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(CAG-ASTN2/PAPPA)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:318677
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into the locus a CAG ubiquitous promoter, floxed stop cassette, the chimeric antisense for human ASTN2 and PAPPA. The final allele lacks a self-excising neomycin resistance cassette. (J:318677)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:318677 Luo Y, et al., Generation and Application of Inducible Chimeric RNA ASTN2-PAPPAas Knockin Mouse Model. Cells. 2022 Jan 14;11(2)
• All: 1 reference(s)