Prg2^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prg2^em1Smoc
• Name: proteoglycan 2, bone marrow; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6860614
• Synonyms: Prg2-KO
• Gene: Prg2 Location: Chr2:84810805-84813976 bp, + strand Genetic Position: Chr2, 49.45 cM
• Alliance: Prg2^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 3 of the Prg2 gene was deleted to generate Prg2 knockout mice. (J:238766)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prg2 Mutation: 20 strains or lines available

References

• Original: J:318598 Lu Y, et al., Eosinophil extracellular traps drive asthma progression through neuro-immune signals. Nat Cell Biol. 2021 Oct;23(10):1060-1072
• All: 2 reference(s)