Fstl1^tm1Ajn
Targeted Allele Detail

Summary

• Symbol: Fstl1^tm1Ajn
• Name: follistatin-like 1; targeted mutation 1, Andrew J Nowalk
• MGI ID: MGI:6858119
• Synonyms: fstl-1^fl, FSTL-1 KD
• Gene: Fstl1 Location: Chr16:37597417-37656878 bp, + strand Genetic Position: Chr16, 26.48 cM
• Alliance: Fstl1^tm1Ajn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317832
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Hypomorph)
• Mutation: Insertion
• Mutation details: A 2565 bp insert containing a loxP sequence inserted in exon 1, exon 2, an FRT-flanked neomycin selection cassette, and a loxP site replaced exons 1 and 2. (J:317832)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fstl1 Mutation: 44 strains or lines available

References

• Original: J:317832 Campfield BT, et al., Follistatin-like protein 1 is a critical mediator of experimental Lyme arthritis and the humoral response to Borrelia burgdorferi infection. Microb Pathog. 2014 Aug;73:70-9
• All: 4 reference(s)