Sting1^{tm3.1(STING1)Geno}
Targeted Allele Detail

Summary

• Symbol: Sting1^{tm3.1(STING1)Geno}
• Name: stimulator of interferon response cGAMP interactor 1; targeted mutation 3.1, Genoway
• MGI ID: MGI:6857664
• Synonyms: Tmem173(tm1.1(TMEM173-R232)Geno)
• Gene: Sting1 Location: Chr18:35866732-35873607 bp, - strand Genetic Position: Chr18, 19.23 cM, cytoband B3
• Alliance: Sting1^{tm3.1(STING1)Geno} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317752
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Sting1^{tm3.1(STING1)Geno} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  STING1 (340061)

  Sting1

  (MGI:1919762)

• Mutation details: Full-length human coding sequence was inserted in-frame with the ATG in exon 3. This allele encodes both short and long human TMEM173 isoforms. The final allele lacks the self-excising selection cassette. (J:317752)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sting1 Mutation: 45 strains or lines available

References

• Original: J:317752 Bertaux F, Direct Data Submission for Knock-in Genoway Alleles. MGI Direct Data Submission. 2022
• All: 1 reference(s)