Odaph^em2Jcch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Odaph^em2Jcch
• Name: odontogenesis associated phosphoprotein; endonuclease-mediated mutation 2, Jan Hu
• MGI ID: MGI:6856732
• Synonyms: Odaph^Ins
• Gene: Odaph Location: Chr5:92135332-92143176 bp, + strand Genetic Position: Chr5, 45.68 cM
• Alliance: Odaph^em2Jcch page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Single point mutation
• Mutation details: CRISPR-targeting generated a stop codon at 41 cysteine (TGC) to Stop (TGA), which was predicted to result in loss of function. In this targeting process, one single nucleotide (A) insertion at position 117-118 and deletion of AT/insertion of TGA at position 127-128 occurred which predicts an apartate-to-arginine substitution at codon 40, frameshift, and termination codon at position 57 (NM_001177577.1 c.[117_118insA;127_128delinsTGA]). (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Odaph Mutation: 5 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)